A Digital Human Organism
With all normal physiological, biophysical and biochemical processes. It generates all required indices and signals in the real time mode! Other makers of medical simulation systems resort to signals drawn with a help of graphics processing programs, or artificially inserted and conditionally altered. Our simulator’s signals are generated by corresponding modules of the system in strict conformity with actual processes in a human organism. They are based on laws and regularities described in scientific or teaching literature. No one could have modeled biochemical transformations in an organism before and we have placed the module of biochemical transformations in the core of our system.
PharmaKin application serves to calculate administration, distribution, and excretion properties of drugs in various organs and tissues of the human organism. One of the important tasks of medical simulation is modeling of pharmacokinetic processes, which helps to dose drugs more efficiently. The main task of such modeling is to calculate precise concentration of a drug in various organs and tissues of the human body to implement individual pharmacological therapy with minimal risks of overdosing and side effects, but with maximum efficiency. With the PurePharmaKin system we can calculate administration, distribution, and excretion properties of a drug in various organs and tissues of the human body on the basis of pharmacological properties, identified during clinical tests and recorded in the system’s database.
Even with the best drug supplies, possibility of a normal diet and availability of analyses and self-control, diabetes compensation continues to be a disturbing problem for both patients and physicists. There is a wide range of insulin with different properties, such as duration of action, suction kinetics and dose maintenance period for various patients. Moreover, different methods of drug selection and doses are worked out in compliance with dietary and behavioral habits, as well as taking into account other diseases. Nevertheless, the problem of diabetes compensation is still inadequately addressed today. Therefore, creation of effective automated systems of diabetes compensation is a very pressing and perspective task, successful solution of which can result in serious changes in the organization of all diabetes services altogether.
More than a decade ago we decided to venture a little way past the limits of the possible into a challenging project of creating a digital model of a cell. Four years of hard work and enormous effort from scientists and programmers were crowned with success and on we went – building organs, systems of organs and – an organism as a whole. And now we have a principally new system, a system of the industry’s future, enabling us to bring medical simulation to a much higher level and change the approach to medical education and practice as such. Our simulation technology is unique and as close as possible to real processes taking place in the human organism. It is built in accordance with the ’from bottom to top‘principle: cells – organs – systems – organism. In its basis lies construction of organs and maintenance of their systems, such as hemodynamic, metabolism, breathing, feeding, excretion, etc. Organs are built from working cells and stroma (skeleton). Working cells are filled with cytoplasm, where biochemical transformations occur with substances coming from the blood, as food matters enter the blood flow from the gastrointestinal tract, etc. All processes are described by well-known laws, easy for perception and interpretation. Our technology serves as a background for various high technical education systems in theoretical and practical medicine, high quality training systems and many other systems. Medical simulators based on this technology differ significantly from other simulators and can be used in education, clinical practice and research. With the help of these simulators, doctors will be able to accurately predict the treatment outcome for a concrete patient and introduce some changes by choosing appropriate treatment. This opens virtually unlimited prospects for application of similar systems.